28832-07-7

• 常用中文名：荷包牡丹碱
• 常用英文名：(+)-Dicentrine
• CAS号：28832-07-7
• 分子式：C₂₀H₂₁NO₄
• 分子量：339.385
• 相关类别： 生物化工 植物提取物
• 发布时间：2018-03-17 08:00:00
• 更新时间：2024-01-06 17:13:59
• Dicentrine, (-)- is an aporphinic alkaloid found in several plant species, mainly from Lauraceae family, which showed significant antinociceptive activity in an acute model of visceral pain in mice. It has also been shown to reduce spontaneous nociception and attenuating mechanical and cold hypersensitivity, probably via a TRPA1-dependent mechanism.

名称

• 中文名: 荷包牡丹碱
• 英文名: 5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-10,11-dimethoxy-7-methyl-, (R)
• 中文别名: L-荷包牡丹碱
• 英文别名: (7aS)-10,11-Dimethoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinoline; Dicentrine; DICENTRINE- (+); 5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-10,11-dimethoxy-7-methyl-, (S)-; d-Dicentrine; O-methyl-phanostenine; Eximine; 5H-1,3-Benzodioxolo[6,5,4-de]benzo[g]quinoline, 6,7,7a,8-tetrahydro-10,11-dimethoxy-7-methyl-, (7aS)-; L-DICENTRINE

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 480.7±45.0 °C at 760 mmHg
• 分子式: C₂₀H₂₁NO₄
• 分子量: 339.385
• 闪点: 142.7±25.9 °C
• 精确质量: 339.147064
• PSA: 40.16000
• LogP: 3.98
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.616
• 储存条件: -20°C，密闭，干燥

合成路线

25368-02-9 ~% 28832-07-7

文献：Tomita; Sirai Yakugaku Zasshi, 1943 , vol. 63, p. 233 Chem.Abstr., 1951 , p. 3399

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