Cutamesine

更新时间：2024-01-02 11:19:54

Cutamesine结构式	常用名	Cutamesine	英文名	SA4503
	CAS号	165377-43-5	分子量	368.51200
	密度	N/A	沸点	N/A
	分子式	C₂₃H₃₂N₂O₂	熔点	N/A
	MSDS	N/A	闪点	N/A

中文名	Cutamesine
英文名	1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine
英文别名	更多

描述
相关类别	信号通路 >> G 蛋白偶联受体/G 蛋白 >> Sigma Receptor 研究领域 >> 神经疾病
参考文献	[1]. Matsuno K, et al. Binding properties of SA4503, a novel and selective sigma 1 receptor agonist. Eur J Pharmacol. 1996 Jun 13;306(1-3):271-9. [2]. Minabe Y, et al. Acute and chronic administration of the selective sigma1 receptor agonist SA4503 significantly alters the activity of midbrain dopamine neurons in rats: An in vivo electrophysiological study. Synapse. 1999 Aug;33(2):129-40. [3]. Ono Y, et al. SA4503, a sigma-1 receptor agonist, suppresses motor neuron damage in in vitro and in vivo amyotrophic lateral sclerosis models. Neurosci Lett. 2014 Jan 24;559:174-8.

描述

相关类别

信号通路 >> G 蛋白偶联受体/G 蛋白 >> Sigma Receptor

研究领域 >> 神经疾病

参考文献

[1]. Matsuno K, et al. Binding properties of SA4503, a novel and selective sigma 1 receptor agonist. Eur J Pharmacol. 1996 Jun 13;306(1-3):271-9.

[2]. Minabe Y, et al. Acute and chronic administration of the selective sigma1 receptor agonist SA4503 significantly alters the activity of midbrain dopamine neurons in rats: An in vivo electrophysiological study. Synapse. 1999 Aug;33(2):129-40.

[3]. Ono Y, et al. SA4503, a sigma-1 receptor agonist, suppresses motor neuron damage in in vitro and in vivo amyotrophic lateral sclerosis models. Neurosci Lett. 2014 Jan 24;559:174-8.

分子式	C₂₃H₃₂N₂O₂
分子量	368.51200
精确质量	368.24600
PSA	24.94000
LogP	3.37250
储存条件	2-8℃

苯基丙基哌嗪

55455-92-0

3,4-二甲氧基苯乙基溴

40173-90-8

~86%

Cutamesine

165377-43-5

文献：Li, Yan; Wang, Xia; Zhang, Jinming; Deuther-Conrad, Winnie; Xie, Fang; Zhang, Xiaojun; Liu, Jian; Qiao, Jinping; Cui, Mengchao; Steinbach, Joerg; Brust, Peter; Liu, Boli; Jia, Hongmei Journal of Medicinal Chemistry, 2013 , vol. 56, # 9 p. 3478 - 3491

肉桂酰胺

621-79-4

Cutamesine

165377-43-5

文献：Fujimura, Ken-Ichi; Matsumoto, Junzo; Niwa, Masashi; Kobayashi, Tadayuki; Kawashima, Yoichi; In, Yasuko; Ishida, Toshimasa Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 8 p. 1675 - 1683

β-苯基丙烯酰氯

102-92-1

Cutamesine

165377-43-5

3,4-二甲氧基苯乙胺

120-20-7

Cutamesine

165377-43-5

肉桂酸

621-82-9

Cutamesine

165377-43-5

1-溴-3-苯基丙烷

637-59-2

Cutamesine

165377-43-5

Cutamesine上游产品 7
CAS号55455-92-0 苯基丙基哌嗪 CAS号40173-90-8 3,4-二甲氧基苯乙基溴 CAS号621-79-4 肉桂酰胺 CAS号102-92-1 β-苯基丙烯酰氯
CAS号120-20-7 3,4-二甲氧基苯乙胺 CAS号621-82-9 肉桂酸 CAS号637-59-2 1-溴-3-苯基丙烷
Cutamesine下游产品 0