卡前列素氨基丁三醇

更新时间：2024-01-01 17:58:59

卡前列素氨基丁三醇结构式	常用名	卡前列素氨基丁三醇	英文名	Carboprost tromethamine
	CAS号	58551-69-2	分子量	489.643
	密度	1.153g/cm3	沸点	536.6ºC at 760 mmHg
	分子式	C₂₅H₄₇NO₈	熔点	N/A
	MSDS	N/A	闪点	292.4ºC

卡前列素氨基丁三醇用途

Carboprost tromethamine 是前列腺素 F2α (prostaglandin F2α) 的 15 甲基类似物。Carboprost tromethamine 能有效促进子宫规律性收缩,显著减少产后出血量。

中文名	卡前列素氨基丁三醇
英文名	carboprost tromethamine
中文别名	(Z)-7-[(3R,5S)-3,5-二羟基-2-[(E,3S)-3-羟基-3-甲基辛-1-烯基]环戊基]庚-5-烯酸氨基丁三醇 \| 卡前列腺氨丁三醇
英文别名	更多

描述	Carboprost tromethamine 是前列腺素 F2α (prostaglandin F2α) 的 15 甲基类似物。Carboprost tromethamine 能有效促进子宫规律性收缩,显著减少产后出血量。
相关类别	研究领域 >> 内分泌信号通路 >> G 蛋白偶联受体/G 蛋白 >> 前列腺素受体
体内研究	卡前列素氨丁三醇对预防剖宫产产后出血有显著作用,对改善高凝状态、维持血流动力学稳定有显著作用。卡前列素氨丁三醇治疗因子宫收缩乏力而持续出血的成功率为84-96%。
参考文献	[1]. Ling Z, et al. Effect of carboprost tromethamine in prevention of postpartum hemorrhage in cesarean section. Pak J Pharm Sci. 2018 Sep;31(5(Special)):2257-2262. [2]. Bai J, et al. A comparison of oxytocin and carboprost tromethamine in the prevention of postpartum hemorrhage in high-risk patients undergoing cesarean delivery. Exp Ther Med. 2014 Jan;7(1):46-50. Epub 2013 Nov 1.

密度	1.153g/cm3
沸点	536.6ºC at 760 mmHg
分子式	C₂₅H₄₇NO₈
分子量	489.643
闪点	292.4ºC
精确质量	489.330170
PSA	184.70000
LogP	1.79410
储存条件	2-8°C，密闭，干燥
水溶解性	Soluble in water.

卡前列素氨基丁三醇毒性英文版

危险品运输编码	NONH for all modes of transport

[The use of prostaglandin F2alpha (Prostin 15M) for terminationof second trimester pregnancy].

Akush. Ginekol. (Sofiia.) 52(2) , 53-5, (2013)

The authors describe a case of terminating a second trimester pregnancy in 21 gestational weeks with use of Prostin 15 M. The patient come to the clinic in 21 gestational week with spontaneous rupture...

[Application of Pfizer drugs in the obstetrics and gynecology practice].

Akush. Ginekol. (Sofiia.) 48 Suppl 1 , 41-4, (2009)

[Some possibilities for application of Pfizer medicines--Prostin 15m, Prostin E2, Prepidil gel, Dostinex, Synarel--in the obstetrician practice].

Akush. Ginekol. (Sofiia.) 46 Suppl 2 , 57-60, (2007)

The authors make a clinical and pharmacological overview of the possibilities of application in the obstetrician practice of part of the medicines of the company Pfiser. Some of these medicines have n...

(Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-(3S)-3-hydroxy-3-methyl-1-octenyl)cyclopentyl)-5-heptenoic acid compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)

(5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic acid - 2-amino-2-(hydroxymethyl)propane-1,3-diol (1:1)

(15S)-15-Methylprostaglandin F2a Tromethamine

(5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic acid - 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)

(5Z)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-3-methyloct-1-en-1-yl]cyclopentyl}hept-5-ensäure--2-amino-2-(hydroxymethyl)propan-1,3-diol(1:1)

Hemabate

Prostin/15M

acide (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-3-méthyloct-1-én-1-yl]cyclopentyl}hept-5-énoïque - 2-amino-2-(hydroxyméthyl)propane-1,3-diol (1:1)

Carboprost tromethamine salt

15(S)15-Methyl pgf2a Tromethamine Salt

Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-15-methyl-, (5Z,9α,11α,13E,15S)-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)

(5Z,9a,11a,13E,15S)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic Acid compd. with 2-Amino-2-(hydroxymethyl)-1,3-propanediol (1:1)

Carboprost trometamol

Carboprost tromethamine

U 32921E

(5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-3-methyloct-1-en-1-yl]cyclopentyl}hept-5-enoic acid - 2-amino-2-(hydroxymethyl)propane-1,3-diol (1:1)