Antide
Antide structure
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Common Name | Antide | ||
|---|---|---|---|---|
| CAS Number | 112568-12-4 | Molecular Weight | 1591.293 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 1798.0±65.0 °C at 760 mmHg | |
| Molecular Formula | C82H108ClN17O14 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 1041.2±34.3 °C | |
| Symbol |
GHS08 |
Signal Word | Danger | |
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Nuclear maturation and structural components of nonhuman primate cumulus-oocyte complexes during in vivo and in vitro maturation.
Fertil. Steril. 91(5 Suppl) , 2043-50, (2009) To compare cumulus cell structure and timing of oocyte maturation of in vitro-matured (IVM) and in vivo-matured (VVM) nonhuman primate oocytes.In vivo maturation and in vitro maturation of oocytes.Animal cell culture laboratory.Forty-eight female rhesus macaq... |
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Effects of suppressing gonadal hormones on response to novel objects in adolescent rats
Horm. Behav. 60(5) , 625-31, (2011) Human adolescents exhibit higher levels of novelty-seeking behaviour than younger or older individuals, and novelty-seeking is higher in males than females from adolescence onwards. Gonadal hormones, such as testosterone and estradiol, have been suggested to ... |
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Expression of type I GNRH receptor and in vivo and in vitro GNRH-I effects in corpora lutea of pseudopregnant rabbits.
J. Endocrinol. 207(3) , 289-300, (2010) The expression of type I GNRH receptor (GNRHR-I) and the direct role of GNRH-I on corpora lutea (CL) function were studied in the pseudopregnant rabbit model. Immunohistochemistry evidenced GNRHR-I and GNRH-I in luteal cells at early (day 4 pseudopregnancy)-,... |
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Plasma membrane expression of GnRH receptors: regulation by antagonists in breast, prostate, and gonadotrope cell lines.
J. Endocrinol. 196(2) , 353-67, (2008) In heterologous expression systems, human GnRH receptors (hGnRHRs) are poorly expressed at the cell surface and this may reflect inefficient exit from the endoplasmic reticulum. Here, we have defined the proportion of GnRHRs at the cell surface using a novel ... |
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Low luteinizing hormone enhances spatial memory and has protective effects on memory loss in rats.
Horm. Behav. 58(5) , 705-13, (2010) Though several studies have suggested that estradiol improves hippocampal-dependent spatial memory, the effects of other hormones in the hypothalamic-pituitary-gonadal axis on memory have largely been ignored. Estradiol and luteinizing hormone (LH) are genera... |
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The mechanism responsible for the supraphysiologic gonadotropin surge in females treated with gonadotropin-releasing hormone (GnRH) agonist and primed with GnRH antagonist.
Fertil. Steril. 93(5) , 1668-75, (2010) To elucidate the physiologic mechanism responsible for the supraphysiologic gonadotropin release from the pituitary induced by gonadotropin-releasing hormone (GnRH) agonist in female rats primed with GnRH antagonist.Controlled experimental intervention.Govern... |
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Plasma membrane expression of gonadotropin-releasing hormone receptors: regulation by peptide and nonpeptide antagonists.
Mol. Endocrinol. 24(2) , 423-35, (2010) Gonadotropin-releasing hormone acts via cell surface receptors but most human (h) GnRH receptors (GnRHRs) are intracellular. A membrane-permeant nonpeptide antagonist [(2S)-2-[5-[2-(2-axabicyclo[2.2.2]oct-2-yl)-1,1-dimethy-2-oxoethyl]-2-(3,5-dimethylphenyl)-1... |
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Regulation of ovarian angiogenesis and apoptosis by GnRH-I analogs.
Mol. Reprod. Dev. 75(4) , 623-31, (2008) An adequate vascular supply is important to provide endocrine and paracrine signals during follicular development. We evaluated the direct in vivo effects of both the GnRH-agonist Leuprolide acetate (LA) and the GnRH-antagonist Antide (Ant) on the expression ... |
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Ubiquitination as a priming process of PKC alpha and PKC epsilon degradation in the alphaT3-1 gonadotrope cell line.
Neuroendocrinology 89(3) , 252-66, (2009) Protein kinase C (PKC) is a family of isoenzymes playing a key role in the regulation of gonadotrope cell functions. Specific PKC isoforms are activated and downregulated differentially by gonadotropin-releasing hormone (GnRH) and the phorbol ester TPA. In th... |
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Leptin facilitates lordosis behavior through GnRH-1 and progestin receptors in estrogen-primed rats.
Neuropeptides 45(1) , 63-7, (2011) Dose response curves for leptin facilitation of estrous behavior (lordosis and proceptivity) were made by infusing the peptide into the lateral ventricle (icv) of ovariectomized (ovx), ad libitum-fed rats injected 40h previously with 5μg of estradiol benzoate... |