Topoisomerase I inhibitor 7

Modify Date: 2024-01-10 15:11:14

Topoisomerase I inhibitor 7 structure	Common Name	Topoisomerase I inhibitor 7
	CAS Number	2408639-81-4	Molecular Weight	405.40
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₁₉N₃O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Topoisomerase I inhibitor 7

Topoisomerase I inhibitor 7 (Compound 8) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 7 significantly inhibits tumor growth (up to 79%) and increases the lifespan (153%) of mice bearing P388 lymphoma transplants. Topoisomerase I inhibitor 7 indicates prospects for further search of new antitumor drug candidates among the heteroarene-fused anthraquinones[1].

Name	Topoisomerase I inhibitor 7

Description	Topoisomerase I inhibitor 7 (Compound 8) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 7 significantly inhibits tumor growth (up to 79%) and increases the lifespan (153%) of mice bearing P388 lymphoma transplants. Topoisomerase I inhibitor 7 indicates prospects for further search of new antitumor drug candidates among the heteroarene-fused anthraquinones[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase
References	[1]. Tikhomirov AS, et al. Amides of pyrrole- and thiophene-fused anthraquinone derivatives: A role of the heterocyclic core in antitumor properties. Eur J Med Chem. 2020 Aug 1;199:112294.

Molecular Formula	C₂₂H₁₉N₃O₅
Molecular Weight	405.40

Topoisomerase I inhibitor 7

Use of Topoisomerase I inhibitor 7

Names

Topoisomerase I inhibitor 7 Biological Activity

Chemical & Physical Properties