CDK7-IN-11

Modify Date: 2024-04-05 22:09:25

CDK7-IN-11 structure	Common Name	CDK7-IN-11
	CAS Number	2414896-32-3	Molecular Weight	488.60
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₂₈N₆O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CDK7-IN-11

CDK7-IN-11 is an orally active CDK7 inhibitor. CDK7-IN-11 exhibits high CDK7 inhibitory activity with IC50 value of 4.2 nM. CDK7-IN-11 can be effectively used for the research of diseases associated with CDK7[1].

Name	CDK7-IN-11

Description	CDK7-IN-11 is an orally active CDK7 inhibitor. CDK7-IN-11 exhibits high CDK7 inhibitory activity with IC50 value of 4.2 nM. CDK7-IN-11 can be effectively used for the research of diseases associated with CDK7[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> CDK
Target	CDK7:4.2 nM (IC50)
In Vitro	CDK7-IN-11 (example 5) has inhibitory activity for CDK7 with IC50 value of 4.2 nM[1]. CDK7-IN-11 (72 h) inhibits cell proliferation in MDA-MB-468 cells and HepG2 cells with IC50 values of 14.0 nM and 3.0 nM[1]. Cell Proliferation Assay[1] Cell Line: MDA-MB-468 cells, HepG2 cells Concentration: Incubation Time: 72 h Result: Showed antiproliferative effect in cells.
References	[1]. Novel cdk7 inhibitory compound or pharmaceutically acceptable salt thereof. Patent. WO2021182914A1.

Molecular Formula	C₂₆H₂₈N₆O₂S
Molecular Weight	488.60