(S)-Carvedilol-d4

Modify Date: 2024-01-29 16:24:27

(S)-Carvedilol-d4 Structure
(S)-Carvedilol-d4 structure
Common Name (S)-Carvedilol-d4
CAS Number 2747915-23-5 Molecular Weight 410.50
Density N/A Boiling Point N/A
Molecular Formula C24H22D4N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (S)-Carvedilol-d4


(S)-Carvedilol-d4 is deuterium labeled (S)-Carvedilol. (S)-Carvedilol, the S-enantiomer of Carvedilol, is a non-selective β/α-1 blocker. (S)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX)[1].

 Names

Name (S)-Carvedilol-d4

 (S)-Carvedilol-d4 Biological Activity

Description (S)-Carvedilol-d4 is deuterium labeled (S)-Carvedilol. (S)-Carvedilol, the S-enantiomer of Carvedilol, is a non-selective β/α-1 blocker. (S)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX)[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Wu T, et al. Protective effects of S-carvedilol on doxorubicin-induced damages to human umbilical vein endothelial cells and rats. J Appl Toxicol. 2019 Aug;39(8):1233-1244.

 Chemical & Physical Properties

Molecular Formula C24H22D4N2O4
Molecular Weight 410.50