5'-DMTr-2,2'-anhydrothymidine

Modify Date: 2024-01-06 22:47:35

5'-DMTr-2,2'-anhydrothymidine Structure
5'-DMTr-2,2'-anhydrothymidine structure
Common Name 5'-DMTr-2,2'-anhydrothymidine
CAS Number 817623-11-3 Molecular Weight 542.58
Density N/A Boiling Point N/A
Molecular Formula C31H30N2O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5'-DMTr-2,2'-anhydrothymidine


5'-DMTr-2,2'-anhydrothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 5'-DMTr-2,2'-anhydrothymidine
Synonym More Synonyms

 5'-DMTr-2,2'-anhydrothymidine Biological Activity

Description 5'-DMTr-2,2'-anhydrothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C31H30N2O7
Molecular Weight 542.58
Exact Mass 542.20500
PSA 101.27000
LogP 3.59690

 Precursor & DownStream

Precursor  0

DownStream  2

 Synonyms

2,2'-anhydro-1-[2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-arabinofuranosyl-5-methyluridine]