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6472-91-9

6472-91-9 structure
6472-91-9 structure
  • Name: CHRYSAMINE G
  • Chemical Name: chrysamine g
  • CAS Number: 6472-91-9
  • Molecular Formula: C26H16N4Na2O6
  • Molecular Weight: 526.40800
  • Create Date: 2018-12-28 18:02:45
  • Modify Date: 2024-01-09 17:23:49
  • Chrysamine G, a carboxylic acid analogue of Congo Red, can be used as a probe of amyloid deposition in Alzheimer's disease. Chrysamine G also can inhibit Aβ-induced toxicity in PC12 cells[1][2].

Name chrysamine g
Synonyms C.I.Direct Yellow 1
Chrysamin-G
CHRYSAMINE
6,6'-dihydroxy-3,3'-biphenyl-4,4'-diyl-bis-azo-dibenzoic acid disodium salt
6,6'-Dihydroxy-3,3'-biphenyl-4,4'-diylbisazo-di-benzoesaeure,Dinatrium-Salz
Description Chrysamine G, a carboxylic acid analogue of Congo Red, can be used as a probe of amyloid deposition in Alzheimer's disease. Chrysamine G also can inhibit Aβ-induced toxicity in PC12 cells[1][2].
Related Catalog
References

[1]. Klunk WE, et, al. Chrysamine-G binding to Alzheimer and control brain: autopsy study of a new amyloid probe. Neurobiol Aging. Jul-Aug 1995;16(4):541-8.

[2]. Klunk WE, et, al. Chrysamine-G, a lipophilic analogue of Congo red, inhibits A beta-induced toxicity in PC12 cells. Life Sci. 1998;63(20):1807-14.

Boiling Point 711.3ºC at 760 mmHg
Molecular Formula C26H16N4Na2O6
Molecular Weight 526.40800
Flash Point 384ºC
Exact Mass 526.08700
PSA 170.16000
LogP 4.32260
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport

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6472-91-9 structure

6472-91-9

Literature: European Journal of Medicinal Chemistry, , vol. 38, # 6 p. 567 - 579

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6472-91-9 structure

6472-91-9

Literature: Trans.electroch.Soc., , vol. 75, p. 377,381
Precursor  3

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