Name | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(2,2,3,3,5,5,6,6-octadeuteriomorpholin-4-yl)propoxy]quinazolin-4-amine |
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Description | Gefitinib D8 (ZD1839 D8) is a deuterium labeled Gefitinib. Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells[1][2]. |
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Related Catalog | |
Target |
IC50: 37 nM (Tyr1173 site, in NR6wtEGFR cells), 37 nM (Tyr992 site, in NR6wtEGFR cells)[1] |
References |
Molecular Formula | C22H16D8ClFN4O3 |
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Molecular Weight | 454.95200 |
Exact Mass | 454.20200 |
PSA | 68.74000 |
LogP | 4.28650 |