119386-39-9

119386-39-9 structure

Name: LYS-LYS-ARG-ALA-ALA-ARG-ALA-THR-SER-NH2
Chemical Name: h-lys-lys-arg-ala-ala-arg-ala-thr-ser-nh2
CAS Number: 119386-39-9
Molecular Formula: C₄₀H₇₈N₁₈O₁₁
Molecular Weight: 987.16100
Catalog: Research Areas Cancer
Create Date: 2018-11-22 12:42:33
Modify Date: 2024-01-11 19:26:09
Myosin light chain kinase fragment 11-19 amide (MLCK(11-19) amide) is a substrate-specific peptide inhibitor of MLCK. Myosin light chain kinase fragment 11-19 amide inhibits hypotonicity-induced Ca2+ entry. Myosin light chain kinase fragment 11-19 amide can be used in the research of human cervical cancer[1][2].

Name	h-lys-lys-arg-ala-ala-arg-ala-thr-ser-nh2
Synonyms	MYOSIN KINASE INHIBITING PEPTIDE Myosin Light Chain Kinase Fragment 11-19 amide LYS-LYS-ARG-ALA-ALA-ARG-ALA-THR-SER-AMIDE LYS-LYS-ARG-ALA-ALA-ARG-ALA-THR-SER-NH2 KKRAARATS-NH2 myosin light chain kinase fragment 11-19 amide MYOSIN LIGHT CHAIN KINASE (11-19) AMIDE

Description	Myosin light chain kinase fragment 11-19 amide (MLCK(11-19) amide) is a substrate-specific peptide inhibitor of MLCK. Myosin light chain kinase fragment 11-19 amide inhibits hypotonicity-induced Ca2+ entry. Myosin light chain kinase fragment 11-19 amide can be used in the research of human cervical cancer[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	MLCK[1]
In Vitro	Myosin light chain kinase fragment 11-19 amide (5 μM) reduces the amplitude and rate of activation of noradrenaline-evoked non-selective cation current (Icat) in rabbit portal vein myocytes[1]. Myosin light chain kinase fragment 11-19 amide inhibits swelling-activated taurine transport with an IC50 value of 2.0 µM[2]. Myosin light chain kinase fragment 11-19 amide (10 µM) inhibits β2-integrin-mediated adhesion in neutrophils treated with KT5720 (25 µM)[3].

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