Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Sudan I
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Sudan I
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DC Chemicals Limited
China
Product Name: Sudan I
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Sudan I
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
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842-07-9

842-07-9 structure

Name: Sudan I
Chemical Name: Sudan I
CAS Number: 842-07-9
Molecular Formula: C₁₆H₁₂N₂O
Molecular Weight: 248.279
Catalog: Dyes and pigments dye Solvent dye
Create Date: 2018-06-12 07:58:17
Modify Date: 2024-01-02 09:32:05
Sudan I is an organic compound, typically classified as an azo dye.

Name	Sudan I
Synonyms	Sudan J 2-Naphthalenol, 1- (phenylazo)- 2-naphthalenol, 1-[(E)-phenylazo]- MFCD00003911 1-(2-phenyldiaz-1-enyl)-2-naphthol Carminaph 1-(Phenyldiazenyl)-2-naphthol Soudan I 2-Naphthalenol, 1-(2-phenyldiazenyl)- SCARLET B 1-[(E)-phenyldiazenyl]naphthalen-2-ol EINECS 212-668-2 SUDAN 1 1-phenylazo-naphthalen-2-ol 2-Naphthalenol, 1-[(E)-2-phenyldiazenyl]- C.I. Solvent Yellow 14 benzene-1-azo-2-naphthol SUDAN 1-[(E)-Phenyldiazenyl]-2-naphthol 2-phenylazo-naphthalen-1-ol 1-benzeneazo-2-naphthol 1-(Phenylazo)-2-naphthol 1-Phenylazo-β-naphthol

Description	Sudan I is an organic compound, typically classified as an azo dye.
Related Catalog	Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others
In Vitro	Sudan I is a monoazo dye with the chemical formula of 1-phenylazo-2-naphthol. Sudan I can cause tumors in the liver or urinary bladder in mammals and is a potential mutagen and carcinogen for humans. Sudan I induces genotoxic effect in HepG2 cells and increases mutagenic and clastogenic effects in the MCL-5 cell lines compared to the AHH-1 cell line. In addition, Sudan I also gives positive results in Salmonella Typhimurium mutagenicity tests with S9 activation, a post-mitochondrial fraction prepared from the livers of rats[1].
References	[1]. Pan H, et al. Evaluation of impact of exposure of Sudan azo dyes and their metabolites on human intestinal bacteria. Anaerobe. 2012 Aug;18(4):445-53.

Density	1.2±0.1 g/cm3
Boiling Point	443.7±28.0 °C at 760 mmHg
Melting Point	131-133 °C
Molecular Formula	C₁₆H₁₂N₂O
Molecular Weight	248.279
Flash Point	290.2±13.3 °C
Exact Mass	248.094955
PSA	44.95000
LogP	4.24
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.634
Water Solubility	0.5 g/L (30 ºC)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QL4900000

CHEMICAL NAME :: 2-Naphthol, 1-(phenylazo)-

CAS REGISTRY NUMBER :: 842-07-9

BEILSTEIN REFERENCE NO. :: 0651992

LAST UPDATED :: 199710

DATA ITEMS CITED :: 26

MOLECULAR FORMULA :: C16-H12-N2-O

MOLECULAR WEIGHT :: 248.30

WISWESSER LINE NOTATION :: L66J BNUNR& CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4200 mg/kg/14D-C

TOXIC EFFECTS :: Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 87360 mg/kg/13W-C

TOXIC EFFECTS :: Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10815 mg/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Liver - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 21630 mg/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Liver - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6000 mg/kg/57W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Implant

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Implant

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 75 mg/kg

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Implant

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 96 mg/kg

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: Unscheduled DNA synthesis

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 8200 ug/L

REFERENCE :: SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 236,933,1987 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,225,1975 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,225,1975 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,6,1971 TOXICOLOGY REVIEW ADCSAJ Advances in Chemistry Series. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) No.1- 1950- Volume(issue)/page/year: 13,271,1970 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M2105 No. of Facilities: 1715 (estimated) No. of Industries: 34 No. of Occupations: 32 No. of Employees: 44358 (estimated) No. of Female Employees: 6755 (estimated)

Symbol	GHS07, GHS08
Signal Word	Warning
Hazard Statements	H317-H341-H351-H413
Precautionary Statements	P280
Hazard Codes	Xn:Harmful;
Risk Phrases	R40;R43;R53;R68
Safety Phrases	S61-S46-S36/37-S22
RIDADR	NONH for all modes of transport
RTECS	QL4900000
HS Code	2928000090

Precursor 7
135-19-3 100-34-5 142-04-1 14580-01-9
53101-94-3 102-07-8 3639-37-0
DownStream 9
4743-58-2 100-02-7 550-60-7 606-79-1
88-75-5 2036-46-6 103-72-0 2834-92-6
612-40-8

HS Code	2928000090
Summary	2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

842-07-9	40339-35-3
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752211-63-5	1014689-18-9
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