Sudan I

Modify Date: 2024-01-02 09:32:05

Sudan I structure	Common Name	Sudan I
	CAS Number	842-07-9	Molecular Weight	248.279
	Density	1.2±0.1 g/cm3	Boiling Point	443.7±28.0 °C at 760 mmHg
	Molecular Formula	C₁₆H₁₂N₂O	Melting Point	131-133 °C
	MSDS	Chinese USA	Flash Point	290.2±13.3 °C
	Symbol	GHS07, GHS08	Signal Word	Warning

Use of Sudan I

Sudan I is an organic compound, typically classified as an azo dye.

Name	Sudan I
Synonym	More Synonyms

Description	Sudan I is an organic compound, typically classified as an azo dye.
Related Catalog	Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others
In Vitro	Sudan I is a monoazo dye with the chemical formula of 1-phenylazo-2-naphthol. Sudan I can cause tumors in the liver or urinary bladder in mammals and is a potential mutagen and carcinogen for humans. Sudan I induces genotoxic effect in HepG2 cells and increases mutagenic and clastogenic effects in the MCL-5 cell lines compared to the AHH-1 cell line. In addition, Sudan I also gives positive results in Salmonella Typhimurium mutagenicity tests with S9 activation, a post-mitochondrial fraction prepared from the livers of rats[1].
References	[1]. Pan H, et al. Evaluation of impact of exposure of Sudan azo dyes and their metabolites on human intestinal bacteria. Anaerobe. 2012 Aug;18(4):445-53.

Density	1.2±0.1 g/cm3
Boiling Point	443.7±28.0 °C at 760 mmHg
Melting Point	131-133 °C
Molecular Formula	C₁₆H₁₂N₂O
Molecular Weight	248.279
Flash Point	290.2±13.3 °C
Exact Mass	248.094955
PSA	44.95000
LogP	4.24
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.634
Water Solubility	0.5 g/L (30 ºC)

Sudan I MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QL4900000

CHEMICAL NAME :: 2-Naphthol, 1-(phenylazo)-

CAS REGISTRY NUMBER :: 842-07-9

BEILSTEIN REFERENCE NO. :: 0651992

LAST UPDATED :: 199710

DATA ITEMS CITED :: 26

MOLECULAR FORMULA :: C16-H12-N2-O

MOLECULAR WEIGHT :: 248.30

WISWESSER LINE NOTATION :: L66J BNUNR& CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4200 mg/kg/14D-C

TOXIC EFFECTS :: Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 87360 mg/kg/13W-C

TOXIC EFFECTS :: Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10815 mg/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Liver - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 21630 mg/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Liver - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6000 mg/kg/57W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Implant

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Implant

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 75 mg/kg

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Implant

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 96 mg/kg

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: Unscheduled DNA synthesis

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 8200 ug/L

REFERENCE :: SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 236,933,1987 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,225,1975 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,225,1975 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,6,1971 TOXICOLOGY REVIEW ADCSAJ Advances in Chemistry Series. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) No.1- 1950- Volume(issue)/page/year: 13,271,1970 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M2105 No. of Facilities: 1715 (estimated) No. of Industries: 34 No. of Occupations: 32 No. of Employees: 44358 (estimated) No. of Female Employees: 6755 (estimated)

Symbol	GHS07, GHS08
Signal Word	Warning
Hazard Statements	H317-H341-H351-H413
Precautionary Statements	P280
Hazard Codes	Xn:Harmful;
Risk Phrases	R40;R43;R53;R68
Safety Phrases	S61-S46-S36/37-S22
RIDADR	NONH for all modes of transport
RTECS	QL4900000
HS Code	2928000090

Precursor 7
CAS#:135-19-3 2-Naphthol CAS#:100-34-5 Benzenediazoniu... CAS#:142-04-1 Anilinium chloride CAS#:14580-01-9 Butanedioic aci...
CAS#:53101-94-3 N-phenyl-N′-(py... CAS#:102-07-8 1,3-Diphenylurea CAS#:3639-37-0 1,3-diphenyl tr...
DownStream 9
CAS#:4743-58-2 Phthalide-3-Ace... CAS#:100-02-7 4-Nitrophenol CAS#:550-60-7 1-Nitro-2-naphthol CAS#:606-79-1 1,6-dinitronaph...
CAS#:88-75-5 o-Nitrophenol CAS#:2036-46-6 (2-methoxynapht... CAS#:103-72-0 Phenyl isothioc... CAS#:2834-92-6 1-Amino-2-naphthol
CAS#:612-40-8 Benzoic acid,2-...

HS Code	2928000090
Summary	2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Development and validation of a confirmatory HPLC method for simultaneous determination of Sudan dyes in animal tissues and eggs.

J. Chromatogr. Sci. 48(1) , 63-7, (2010)

A simple and sensitive high-performance liquid chromatography (HPLC) analytical method for the simultaneous determination of six Sudan dyes (Sudan Red G, Sudan I, Sudan II, Sudan III, Sudan Red 7B, Su...

Solubilization of two organic dyes by cationic ester-containing gemini surfactants.

J. Colloid. Interface Sci. 376(1) , 112-8, (2012)

Solubilization of two different types of organic dyes, Quinizarin with an anthraquinone structure and Sudan I with an azo structure, has been studied in aqueous solutions of a series of cationic gemin...

Accelerated removal of Sudan dye by Shewanella oneidensis MR-1 in the presence of quinones and humic acids.

World J. Microbiol. Biotechnol. 29(9) , 1723-30, (2013)

Although there have been many studies on bacterial removal of soluble azo dyes, much less information is available for biological treatment of water-insoluble azo dyes. The few bacterial species capab...

Sudan J

2-Naphthalenol, 1- (phenylazo)-

2-naphthalenol, 1-[(E)-phenylazo]-

MFCD00003911

1-(2-phenyldiaz-1-enyl)-2-naphthol

Carminaph

1-(Phenyldiazenyl)-2-naphthol

Soudan I

2-Naphthalenol, 1-(2-phenyldiazenyl)-

SCARLET B

1-[(E)-phenyldiazenyl]naphthalen-2-ol

EINECS 212-668-2

SUDAN 1

1-phenylazo-naphthalen-2-ol

2-Naphthalenol, 1-[(E)-2-phenyldiazenyl]-

C.I. Solvent Yellow 14

benzene-1-azo-2-naphthol

SUDAN

1-[(E)-Phenyldiazenyl]-2-naphthol

2-phenylazo-naphthalen-1-ol

1-benzeneazo-2-naphthol

1-(Phenylazo)-2-naphthol

1-Phenylazo-β-naphthol

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Sudan I
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Sudan I
Price: ￥108.0/100g ￥228.0/20mg
Purity: 98.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Sudan I
Price: $280.0/20mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Sudan I
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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Sudan I

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