CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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QK4250000
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CHEMICAL NAME :
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2-Naphthalenol, 1-((4-(phenylazo)phenyl)azo)-
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CAS REGISTRY NUMBER :
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85-86-9
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BEILSTEIN REFERENCE NO. :
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0931185
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LAST UPDATED :
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199701
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DATA ITEMS CITED :
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12
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MOLECULAR FORMULA :
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C22-H16-N4-O
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MOLECULAR WEIGHT :
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352.42
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WISWESSER LINE NOTATION :
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L66J BNUNR DNUNR&& CQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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250 mg/kg
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TOXIC EFFECTS :
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Liver - hepatitis (hepatocellular necrosis), diffuse Liver - hepatitis (hepatocellular necrosis), zonal Liver - hepatitis, fibrous (cirrhosis, post-necrotic scarring)
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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1 gm/kg
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TOXIC EFFECTS :
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Liver - hepatitis (hepatocellular necrosis), diffuse Liver - hepatitis (hepatocellular necrosis), zonal Liver - hepatitis, fibrous (cirrhosis, post-necrotic scarring)
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Intrapleural
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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500 mg/kg
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TOXIC EFFECTS :
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Liver - hepatitis (hepatocellular necrosis), diffuse Liver - hepatitis (hepatocellular necrosis), zonal Liver - hepatitis, fibrous (cirrhosis, post-necrotic scarring)
MUTATION DATA
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TYPE OF TEST :
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Cytogenetic analysis
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TEST SYSTEM :
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Rodent - hamster Ovary
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DOSE/DURATION :
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20 umol/L/5H (Continuous)
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REFERENCE :
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ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 1,27,1979 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,241,1975 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,241,1975 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81045 No. of Facilities: 650 (estimated) No. of Industries: 8 No. of Occupations: 16 No. of Employees: 5334 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81045 No. of Facilities: 437 (estimated) No. of Industries: 3 No. of Occupations: 7 No. of Employees: 7807 (estimated) No. of Female Employees: 5186 (estimated)
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