Sudan IV

Modify Date: 2024-01-01 22:29:31

Sudan IV Structure
Sudan IV structure
Common Name Sudan IV
CAS Number 85-83-6 Molecular Weight 380.442
Density 1.2±0.1 g/cm3 Boiling Point 618.8±55.0 °C at 760 mmHg
Molecular Formula C24H20N4O Melting Point 199ºC
MSDS Chinese USA Flash Point 424.4±20.8 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of Sudan IV


Sudan IV is a lysochrome (fat-soluble dye) diazo dye used for the staining of lipids, triglycerides and lipoproteins on frozen paraffin sections[1].

 Names

Name sudan IV
Synonym More Synonyms

 Sudan IV Biological Activity

Description Sudan IV is a lysochrome (fat-soluble dye) diazo dye used for the staining of lipids, triglycerides and lipoproteins on frozen paraffin sections[1].
Related Catalog
References

[1]. Refat NA, et al. The induction of cytochrome P450 1A1 by sudan dyes. J Biochem Mol Toxicol. 2008 Mar-Apr;22(2):77-84.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 618.8±55.0 °C at 760 mmHg
Melting Point 199ºC
Molecular Formula C24H20N4O
Molecular Weight 380.442
Flash Point 424.4±20.8 °C
Exact Mass 380.163696
PSA 69.67000
LogP 6.66
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.645
Water Solubility Insoluble in water; soluble in benzene, methanol, acetone, isopropanol; slightly soluble in ethanol

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QL5775000
CHEMICAL NAME :
2-Naphthol, 1-((4-(o-tolylazo)-o-tolyl)azo)-
CAS REGISTRY NUMBER :
85-83-6
BEILSTEIN REFERENCE NO. :
0709018
LAST UPDATED :
199701
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C24-H20-N4-O
MOLECULAR WEIGHT :
380.48
WISWESSER LINE NOTATION :
L66J BNUNR B1 DNUNR B1&& CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
512 mg/kg/58W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - hamster Embryo
DOSE/DURATION :
100 mg/L
REFERENCE :
AETODY Advances in Modern Environmental Toxicology. (Senate Press, Inc., P.O. Box 252, Princeton Junction, NJ 08550) V.1- 1980- Volume(issue)/page/year: 1,241,1980 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,217,1975 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,217,1975 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1356 No. of Facilities: 212 (estimated) No. of Industries: 6 No. of Occupations: 13 No. of Employees: 2432 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1356 No. of Facilities: 1210 (estimated) No. of Industries: 15 No. of Occupations: 23 No. of Employees: 20219 (estimated) No. of Female Employees: 10256 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;T: Toxic;
Risk Phrases R36/38
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS QL5775000
HS Code 2927000090

 Synthetic Route

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Sudan IV Structure

Sudan IV

CAS#:85-83-6

Literature: Chemische Berichte, , vol. 20, p. 1182

 Customs

HS Code 2927000090
Summary 2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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Development and validation of a confirmatory HPLC method for simultaneous determination of Sudan dyes in animal tissues and eggs.

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 Synonyms

1-({2-Methyl-4-[(2-methylphenyl)diazenyl]phenyl}diazenyl)-2-naphthol
o-Tolylazo-o-tolylazo-β-naphthol
Scarlet Red
2-Naphthalenol, 1-[(E)-2-[2-methyl-4-[(E)-2-(2-methylphenyl)diazenyl]phenyl]diazenyl]-
EINECS 201-635-8
solvent red percent24
1-[(E)-{2-Methyl-4-[(E)-(2-methylphenyl)diazenyl]phenyl}diazenyl]-2-naphthol
fatredb
AKA501
1-[(E)-{2-methyl-4-[(E)-(2-methylphenyl)diazenyl]phenyl}diazenyl]naphthalen-2-ol
Solvent Red 24
MFCD00003893
c.i.258
oilredf
2-Naphthalenol, 1-[2-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl]diazenyl]-
oilredd
2-Naphthol, 1-[[4-(o-tolylazo)-o-tolyl]azo]-
oilreda
L66J BNUNR B1 DNUNR B1&& CQ
o-Tolylazo-o-tolylazo-b-naphthol
C.I. Solvent Red 24 (8CI)
oilred3
1-[[2-Methyl-4-[(2-methylphenyl)azo]phenyl]azo]-2-naphthalenol
2-Naphthalenol, 1-[[2-methyl-4-[(2-methylphenyl)azo]phenyl]azo]-
2-NAPHTHALENOL, 1-((2-METHYL-4-((2-METHYLPHENYL)AZO)PHENYL)AZO)-
sudanp
1-{[2-Methyl-4-(o-tolylazo)phenyl]azo}naphthalen-2-ol
oilred7
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