1353011-95-6
1353011-95-6 structure
- Name: Chloroacetamido-PEG4-NHS ester
- Chemical Name: Chloroacetamido-PEG4-NHS ester
- CAS Number: 1353011-95-6
- Molecular Formula: C17H27ClN2O9
- Molecular Weight: 438.857
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-12-02 10:04:29
- Modify Date: 2024-01-09 21:26:17
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Chloroacetamido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Chloroacetamido-PEG4-NHS ester |
|---|---|
| Synonyms |
2-Chloro-N-{15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}acetamide
Acetamide, 2-chloro-N-[15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]- |
| Description | Chloroacetamido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C17H27ClN2O9 |
| Molecular Weight | 438.857 |
| Exact Mass | 438.140503 |
| LogP | -3.45 |
| Index of Refraction | 1.513 |