Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Iodoacetyl-PEG4-NHS ester
Price:
Purity: 97.0%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: Iodoacetyl-PEG4-NHS ester
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

2517899-65-7

2517899-65-7 structure

2517899-65-7 structure

Name: Iodoacetyl-PEG4-NHS ester
Chemical Name: Iodoacetyl-PEG4-NHS ester
CAS Number: 2517899-65-7
Molecular Formula: C₁₇H₂₇IN₂O₉
Molecular Weight: 530.31
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2021-09-16 09:14:09
Modify Date: 2024-01-08 17:59:50
Iodoacetyl-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Iodoacetyl-PEG4-NHS ester

Description	Iodoacetyl-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₇H₂₇IN₂O₉
Molecular Weight	530.31