1314378-14-7
1314378-14-7 structure
- Name: Fmoc-PEG4-NHS ester
- Chemical Name: 9H-Fluoren-9-ylmethyl {15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}carbamate
- CAS Number: 1314378-14-7
- Molecular Formula: C30H36N2O10
- Molecular Weight: 584.614
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-27 12:14:15
- Modify Date: 2024-09-26 16:43:42
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Fmoc-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 9H-Fluoren-9-ylmethyl {15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}carbamate |
|---|---|
| Synonyms |
Carbamic acid, N-[15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]-, 9H-fluoren-9-ylmethyl ester
9H-Fluoren-9-ylmethyl {15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}carbamate |
| Description | Fmoc-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C30H36N2O10 |
| Molecular Weight | 584.614 |
| Exact Mass | 584.237000 |
| LogP | 0.78 |
| Index of Refraction | 1.590 |
| Storage condition | -20°C |
| Hazard Codes | Xi |
|---|