194413-58-6

194413-58-6 structure
194413-58-6 structure
  • Name: Semaxanib (SU5416)
  • Chemical Name: SeMaxanib
  • CAS Number: 194413-58-6
  • Molecular Formula: C15H14N2O
  • Molecular Weight: 238.28400
  • Catalog: Biochemical Inhibitor Protein tyrosine kinase
  • Create Date: 2016-08-30 09:06:04
  • Modify Date: 2024-01-04 14:25:43
  • (Z)-Semaxanib (compound (z)-1) is a potent tyrosine kinase inhibitor. (Z)-Semaxanib shows cytotoxicity for TAMH and HepG2 cells with IC50s of 6.28 µM and 8.17 µM, respectively[1].

Name SeMaxanib
Synonyms CK 1752A
Sematilide HCl
Sematilide monohydrochloride
SEMATILIDE HYDROCHLORIDE
Semaxanib (SU5416)
Description (Z)-Semaxanib (compound (z)-1) is a potent tyrosine kinase inhibitor. (Z)-Semaxanib shows cytotoxicity for TAMH and HepG2 cells with IC50s of 6.28 µM and 8.17 µM, respectively[1].
Related Catalog
References

[1]. Ngai MH, So CL, Sullivan MB, Ho HK, Chai CL. Photoinduced Isomerization and Hepatoxicities of Semaxanib, Sunitinib and Related 3-Substituted Indolin-2-ones. ChemMedChem. 2016 Jan 5;11(1):72-80.

Density 1.256g/cm3
Boiling Point 481.4ºC at 760mmHg
Melting Point 220-222℃
Molecular Formula C15H14N2O
Molecular Weight 238.28400
Flash Point 244.9ºC
Exact Mass 238.11100
PSA 44.89000
LogP 3.26220
Vapour Pressure 2E-09mmHg at 25°C
Index of Refraction 1.683
Storage condition -20℃