Name | SeMaxanib |
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Synonyms |
CK 1752A
Sematilide HCl Sematilide monohydrochloride SEMATILIDE HYDROCHLORIDE Semaxanib (SU5416) |
Description | (Z)-Semaxanib (compound (z)-1) is a potent tyrosine kinase inhibitor. (Z)-Semaxanib shows cytotoxicity for TAMH and HepG2 cells with IC50s of 6.28 µM and 8.17 µM, respectively[1]. |
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Related Catalog | |
References |
Density | 1.256g/cm3 |
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Boiling Point | 481.4ºC at 760mmHg |
Melting Point | 220-222℃ |
Molecular Formula | C15H14N2O |
Molecular Weight | 238.28400 |
Flash Point | 244.9ºC |
Exact Mass | 238.11100 |
PSA | 44.89000 |
LogP | 3.26220 |
Vapour Pressure | 2E-09mmHg at 25°C |
Index of Refraction | 1.683 |
Storage condition | -20℃ |
~79% 194413-58-6 |
Literature: Blanche, Emilie A.; Maskell, Lesley; Colucci, Marie A.; Whatmore, Jacqueline L.; Moody, Christopher J. Tetrahedron, 2009 , vol. 65, # 25 p. 4894 - 4903 |
~65% 194413-58-6 |
Literature: Lubkoll, Jana; Millemaggi, Alessia; Perry, Alexis; Taylor, Richard J.K. Tetrahedron, 2010 , vol. 66, # 33 p. 6606 - 6612 |
~57% 194413-58-6 |
Literature: Sugen, Inc. Patent: US6846839 B1, 2005 ; |
~19% 194413-58-6 |
Literature: Lubkoll, Jana; Millemaggi, Alessia; Perry, Alexis; Taylor, Richard J.K. Tetrahedron, 2010 , vol. 66, # 33 p. 6606 - 6612 |
Precursor 4 | |
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DownStream 0 |