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774603-04-2

774603-04-2 structure
774603-04-2 structure
  • Name: 10-Nitrolinoleic acid
  • Chemical Name: (9E,12Z)-10-nitrooctadeca-9,12-dienoic acid
  • CAS Number: 774603-04-2
  • Molecular Formula: C18H31NO4
  • Molecular Weight: 325.443
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage PPAR
  • Create Date: 2018-04-14 20:21:59
  • Modify Date: 2024-01-05 11:21:16
  • 10-Nitrolinoleic acid is a potent peroxisome proliferator-activated receptor γ (PPARγ) agonist. 10-Nitrolinoleic acid competes with [3H]Rosiglitazone for binding to PPAR-γ, with an IC50 of 0.22 μM[1].

Name (9E,12Z)-10-nitrooctadeca-9,12-dienoic acid
Synonyms (9E,12Z)-10-Nitro-9,12-octadecadienoic acid
9,12-Octadecadienoic acid, 10-nitro-, (9E,12Z)-
10-nitrolinoleic acid
Description 10-Nitrolinoleic acid is a potent peroxisome proliferator-activated receptor γ (PPARγ) agonist. 10-Nitrolinoleic acid competes with [3H]Rosiglitazone for binding to PPAR-γ, with an IC50 of 0.22 μM[1].
Related Catalog
Target

PPARγ:0.22 μM (IC50)

References

[1]. Dunny E, et, al. Stereocontrolled synthesis of the PPAR-gamma agonist 10-nitrolinoleic acid. J Org Chem. 2010 Aug 6;75(15):5334-6.

Density 1.0±0.1 g/cm3
Boiling Point 452.2±33.0 °C at 760 mmHg
Molecular Formula C18H31NO4
Molecular Weight 325.443
Flash Point 173.9±13.8 °C
Exact Mass 325.225311
PSA 83.12000
LogP 6.10
Vapour Pressure 0.0±2.4 mmHg at 25°C
Index of Refraction 1.493
Storage condition -20℃