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1245823-50-0

1245823-50-0 structure
1245823-50-0 structure
  • Name: Propargyl-PEG4-CH2CH2-Boc
  • Chemical Name: 2-Methyl-2-propanyl 4,7,10,13,16-pentaoxanonadec-18-yn-1-oate
  • CAS Number: 1245823-50-0
  • Molecular Formula: C18H32O7
  • Molecular Weight: 360.443
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
  • Create Date: 2018-07-11 13:11:02
  • Modify Date: 2024-01-31 09:15:01
  • Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based non-cleavable ADC linker. Propargyl-PEG5-Boc can used to synthesize ADC inhibitors of Galectin-3[1].

Name 2-Methyl-2-propanyl 4,7,10,13,16-pentaoxanonadec-18-yn-1-oate
Synonyms MFCD22201534
2-Methyl-2-propanyl 4,7,10,13,16-pentaoxanonadec-18-yn-1-oate
4,7,10,13,16-Pentaoxanonadec-18-yn-1-oic acid, 1,1-dimethylethyl ester
Description Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based non-cleavable ADC linker. Propargyl-PEG5-Boc can used to synthesize ADC inhibitors of Galectin-3[1].
Related Catalog
Target

Non-cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Zhang H, et al. Thiodigalactoside-Bovine Serum Albumin Conjugates as High-Potency Inhibitors of Galectin-3: An Outstanding Example of Multivalent Presentation of Small Molecule Inhibitors. Bioconjug Chem. 2018 Apr 18;29(4):1266-1275.

Density 1.0±0.1 g/cm3
Boiling Point 420.6±40.0 °C at 760 mmHg
Molecular Formula C18H32O7
Molecular Weight 360.443
Flash Point 179.0±27.4 °C
Exact Mass 360.214813
LogP 0.53
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.456
Hazard Codes Xi