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  • DC Chemicals Limited
  • China
  • Product Name: TBDMS-PEG5
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

134179-40-1

134179-40-1 structure
134179-40-1 structure
  • Name: TBDMS-PEG4-OH
  • Chemical Name: 2,2,3,3-Tetramethyl-4,7,10,13-tetraoxa-3-silapentadecan-15-ol
  • CAS Number: 134179-40-1
  • Molecular Formula: C14H32O5Si
  • Molecular Weight: 308.486
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-05 20:37:13
  • Modify Date: 2024-01-11 21:31:42
  • TBDMS-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2,2,3,3-Tetramethyl-4,7,10,13-tetraoxa-3-silapentadecan-15-ol
Synonyms 2,2,3,3-Tetramethyl-4,7,10,13-tetraoxa-3-silapentadecan-15-ol
4,7,10,13-Tetraoxa-3-silapentadecan-15-ol, 2,2,3,3-tetramethyl-
MFCD25424114
Description TBDMS-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.0±0.1 g/cm3
Boiling Point 349.6±27.0 °C at 760 mmHg
Molecular Formula C14H32O5Si
Molecular Weight 308.486
Flash Point 165.2±23.7 °C
Exact Mass 308.201904
LogP 1.42
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.441