1599486-33-5
1599486-33-5 structure
- Name: Mal-PEG6-PFP ester
- Chemical Name: Mal-PEG6-PFP
- CAS Number: 1599486-33-5
- Molecular Formula: C25H30F5NO10
- Molecular Weight: 599.498
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-09 00:42:57
- Modify Date: 2024-01-03 18:12:43
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Mal-PEG6-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Mal-PEG6-PFP |
|---|---|
| Synonyms |
MFCD22683307
3,6,9,12,15,18-Hexaoxaheneicosan-21-oic acid, 1-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,3,4,5,6-pentafluorophenyl ester Pentafluorophenyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18-hexaoxahenicosan-21-oate |
| Description | Mal-PEG6-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 623.0±55.0 °C at 760 mmHg |
| Molecular Formula | C25H30F5NO10 |
| Molecular Weight | 599.498 |
| Flash Point | 330.6±31.5 °C |
| Exact Mass | 599.179016 |
| LogP | 0.57 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.490 |