1643957-26-9

1643957-26-9 structure
1643957-26-9 structure
  • Name: Benzyl-PEG2-CH2-Boc
  • Chemical Name: Benzyl-PEG3-CH2CO2tBu
  • CAS Number: 1643957-26-9
  • Molecular Formula: C17H26O5
  • Molecular Weight: 310.385
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-08 02:38:35
  • Modify Date: 2024-09-17 17:38:48
  • Benzyl-PEG2-CH2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Name Benzyl-PEG3-CH2CO2tBu
Synonyms 2-Methyl-2-propanyl {2-[2-(benzyloxy)ethoxy]ethoxy}acetate
Acetic acid, 2-[2-[2-(phenylmethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
MFCD28122971
Description Benzyl-PEG2-CH2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Ottis P, et al. Assessing Different E3 Ligases for Small Molecule Induced Protein Ubiquitination and Degradation. ACS Chem Biol. 2017 Oct 20;12(10):2570-2578.

Density 1.1±0.1 g/cm3
Boiling Point 396.0±27.0 °C at 760 mmHg
Molecular Formula C17H26O5
Molecular Weight 310.385
Flash Point 170.7±23.8 °C
Exact Mass 310.178009
LogP 2.88
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.488
Hazard Codes Xi