1807518-63-3
1807518-63-3 structure
- Name: Bromo-PEG2-CH2-Boc
- Chemical Name: 2-Methyl-2-propanyl [2-(2-bromoethoxy)ethoxy]acetate
- CAS Number: 1807518-63-3
- Molecular Formula: C10H19BrO4
- Molecular Weight: 283.159
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-14 06:20:14
- Modify Date: 2024-01-27 11:41:30
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Bromo-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-Methyl-2-propanyl [2-(2-bromoethoxy)ethoxy]acetate |
|---|---|
| Synonyms |
2-Methyl-2-propanyl [2-(2-bromoethoxy)ethoxy]acetate
Acetic acid, 2-[2-(2-bromoethoxy)ethoxy]-, 1,1-dimethylethyl ester |
| Description | Bromo-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 316.4±22.0 °C at 760 mmHg |
| Molecular Formula | C10H19BrO4 |
| Molecular Weight | 283.159 |
| Flash Point | 145.2±22.3 °C |
| Exact Mass | 282.046661 |
| LogP | 2.16 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.462 |