2100306-71-4

2100306-71-4 structure
2100306-71-4 structure
  • Name: Bromo-PEG3-CH2CO2tBu
  • Chemical Name: Bromo-PEG3-CH2-Boc
  • CAS Number: 2100306-71-4
  • Molecular Formula: C12H23BrO5
  • Molecular Weight: 327.21
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 15:56:39
  • Modify Date: 2024-01-09 15:06:59
  • Bromo-PEG3-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bromo-PEG3-CH2-Boc
Synonyms MFCD30723231
Description Bromo-PEG3-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C12H23BrO5
Molecular Weight 327.21