2030118-14-8

2030118-14-8 structure

Name: Ald-C2-PEG4-azide
Chemical Name: N3-PEG4-CHO
CAS Number: 2030118-14-8
Molecular Formula: C₁₁H₂₁N₃O₅
Molecular Weight: 275.302
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-20 00:55:52
Modify Date: 2024-01-03 17:30:09
Ald-C2-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N3-PEG4-CHO
Synonyms	N3-PEG4-ALD

Description	Ald-C2-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562