Name | m-PEG10-Tos |
---|
Description | m-PEG10-Tos is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
---|---|
Related Catalog | |
Target |
PEGs |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
[1]. Jennifer Riggs-Sauthier, et al. Oligomer-opioid agonist conjugates. US8575196B2. |
Molecular Formula | C26H46O12S |
---|---|
Molecular Weight | 582.7 |
Storage condition | 2-8°C |