756526-00-8

756526-00-8 structure
756526-00-8 structure
  • Name: CBZ-NH-PEG4-CH2CH2COOH
  • Chemical Name: Z-15-aMino-4,7,10,13-tetraoxapentadecacanoic acid
  • CAS Number: 756526-00-8
  • Molecular Formula: C19H29NO8
  • Molecular Weight: 399.43546
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-13 21:02:27
  • Modify Date: 2024-01-08 17:43:25
  • Cbz-NH-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Z-15-aMino-4,7,10,13-tetraoxapentadecacanoic acid
Synonyms CBZ-NH-PEG4-CH2CH2COOH
Description Cbz-NH-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C19H29NO8
Molecular Weight 399.43546
Hazard Codes Xi