1205751-19-4

1205751-19-4 structure
1205751-19-4 structure
  • Name: Cbz-NH-PEG1-CH2CH2COOH
  • Chemical Name: Cbz-NH-PEG1-CH2CH2COOH
  • CAS Number: 1205751-19-4
  • Molecular Formula: C13H17NO5
  • Molecular Weight: 267.28
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 18:16:34
  • Modify Date: 2024-01-10 11:16:31
  • Cbz-NH-PEG1-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Cbz-NH-PEG1-CH2CH2COOH
Synonyms MFCD14582436
Description Cbz-NH-PEG1-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C13H17NO5
Molecular Weight 267.28
Hazard Codes Xi