1333154-70-3
1333154-70-3 structure
- Name: NHS-PEG4-(m-PEG4)3-ester
- Chemical Name: NHS-PEG4-(m-PEG4)3-ester
- CAS Number: 1333154-70-3
- Molecular Formula: C60H110N6O28
- Molecular Weight: 1363.539
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-06 09:19:25
- Modify Date: 2024-01-08 18:55:23
-
NHS-PEG4-(m-PEG4)3-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | NHS-PEG4-(m-PEG4)3-ester |
|---|---|
| Synonyms |
4,11,14,17,20-Pentaoxa-7,23-diazaoctacosan-1-amide, 28-[(2,5-dioxo-1-pyrrolidinyl)oxy]-8,24,28-trioxo-6,6-bis(5-oxo-2,9,12,15,18-pentaoxa-6-azanonadec-1-yl)-N-3,6,9,12-tetraoxatridec-1-yl-
MFCD22683277 28-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-8,24,28-trioxo-6,6-bis(15-oxo-2,5,8,11,18-pentaoxa-14-azanonadecan-19-yl)-N-(2,5,8,11-tetraoxatridecan-13-yl)-4,11,14,17,20-pentaoxa-7,23-diazaoctacosan-1-amide |
| Description | NHS-PEG4-(m-PEG4)3-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Molecular Formula | C60H110N6O28 |
| Molecular Weight | 1363.539 |
| Exact Mass | 1362.736816 |
| LogP | -8.37 |
| Index of Refraction | 1.515 |