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1449390-68-4

1449390-68-4 structure
1449390-68-4 structure
  • Name: m-PEG4-hydrazide
  • Chemical Name: m-PEG4-Hydrazide
  • CAS Number: 1449390-68-4
  • Molecular Formula: C10H22N2O5
  • Molecular Weight: 250.292
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-07 04:16:14
  • Modify Date: 2024-02-06 00:21:49
  • m-PEG4-Hydrazide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name m-PEG4-Hydrazide
Synonyms MPEG4-HYDRAZIDE
Description m-PEG4-Hydrazide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density 1.1±0.1 g/cm3
Boiling Point 408.1±35.0 °C at 760 mmHg
Molecular Formula C10H22N2O5
Molecular Weight 250.292
Flash Point 200.6±25.9 °C
Exact Mass 250.152878
LogP -2.70
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.459