1443983-36-5
1443983-36-5 structure
- Name: GDC-0927 Racemate
- Chemical Name: GDC-0927 Racemate
- CAS Number: 1443983-36-5
- Molecular Formula: C28H28FNO4
- Molecular Weight: 461.52
- Catalog: Research Areas Cancer
- Create Date: 2019-01-20 19:09:53
- Modify Date: 2024-01-11 10:52:04
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GDC-0927 Racemate (SRN-927 Racemate) is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases.
| Name | GDC-0927 Racemate |
|---|
| Description | GDC-0927 Racemate (SRN-927 Racemate) is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases. |
|---|---|
| Related Catalog | |
| Target |
IC50: 0.2 nM (ER-α)[1] |
| In Vitro | GDC-0927 Racemate (Example 1) is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases. GDC-0927 Racemate reduces the viability of MCF7 cells with an IC50 of 0.21 nM[1]. |
| References |
[1]. Mehmet Kahraman, et al. Estrogen receptor modulator and uses thereof. WO2014205138A1. |
| Molecular Formula | C28H28FNO4 |
|---|---|
| Molecular Weight | 461.52 |
| Storage condition | 2-8℃ |