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1443983-36-5

1443983-36-5 structure
1443983-36-5 structure
  • Name: GDC-0927 Racemate
  • Chemical Name: GDC-0927 Racemate
  • CAS Number: 1443983-36-5
  • Molecular Formula: C28H28FNO4
  • Molecular Weight: 461.52
  • Catalog: Research Areas Cancer
  • Create Date: 2019-01-20 19:09:53
  • Modify Date: 2024-01-11 10:52:04
  • GDC-0927 Racemate (SRN-927 Racemate) is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases.

Name GDC-0927 Racemate
Description GDC-0927 Racemate (SRN-927 Racemate) is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases.
Related Catalog
Target

IC50: 0.2 nM (ER-α)[1]

In Vitro GDC-0927 Racemate (Example 1) is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases. GDC-0927 Racemate reduces the viability of MCF7 cells with an IC50 of 0.21 nM[1].
References

[1]. Mehmet Kahraman, et al. Estrogen receptor modulator and uses thereof. WO2014205138A1.

Molecular Formula C28H28FNO4
Molecular Weight 461.52
Storage condition 2-8℃