1092369-24-8

1092369-24-8 structure

Name: SLF-amido-C2-COOH
Chemical Name: Target Protein-binding moiety 13
CAS Number: 1092369-24-8
Molecular Formula: C₃₄H₄₄N₂O₉
Molecular Weight: 624.72
Catalog: Signaling Pathways PROTAC PROTAC
Create Date: 2019-02-09 06:00:25
Modify Date: 2024-01-13 10:46:49
Target Protein-binding moiety 13 is a synthetic ligand for FKBP (SLF), which is used in the synthesis of PROTACs.

Name	Target Protein-binding moiety 13

Description	Target Protein-binding moiety 13 is a synthetic ligand for FKBP (SLF), which is used in the synthesis of PROTACs.
Related Catalog	Signaling Pathways >> PROTAC >> PROTAC Research Areas >> Cancer
In Vitro	Target Protein-binding moiety 13 (SLF building block 2) is a synthetic ligand for FKBP (SLF). SLF is composed of only one half of FK506 and it is known to have a significantly weaker affinity for FKBP12.
References	[1]. Dunyak BM, et al. Selective Targeting of Cells via Bispecific Molecules That Exploit Coexpression of TwoIntracellular Proteins. ACS Chem Biol. 2015 Nov 20;10(11):2441-7.