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2022182-58-5

2022182-58-5 structure
2022182-58-5 structure
  • Name: Thalidomide-O-amido-C3-NH2
  • Chemical Name: E3 Ligase Ligand-Linker Conjugates 52 (TFA)
  • CAS Number: 2022182-58-5
  • Molecular Formula: C20H21F3N4O8
  • Molecular Weight: 502.40
  • Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
  • Create Date: 2019-10-08 12:46:52
  • Modify Date: 2024-01-14 18:39:35
  • E3 Ligase Ligand-Linker Conjugates 52 TFA (Compound 10) incorporates a CRBN ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 Ligase Ligand-Linker Conjugates 52 TFA (Compound 10) is a PROTAC precursor[1].

Name E3 Ligase Ligand-Linker Conjugates 52 (TFA)
Description E3 Ligase Ligand-Linker Conjugates 52 TFA (Compound 10) incorporates a CRBN ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 Ligase Ligand-Linker Conjugates 52 TFA (Compound 10) is a PROTAC precursor[1].
Related Catalog
Target

Cereblon

References

[1]. Lohbeck J, et al. Practical synthesis of a phthalimide-based Cereblon ligand to enable PROTAC development. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5260-5262.

Molecular Formula C20H21F3N4O8
Molecular Weight 502.40