2152679-62-2

2152679-62-2 structure
2152679-62-2 structure
  • Name: Acid-PEG13-NHS ester
  • Chemical Name: Acid-PEG13-NHS ester
  • CAS Number: 2152679-62-2
  • Molecular Formula: C34H61NO19
  • Molecular Weight: 787.84
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 18:17:46
  • Modify Date: 2024-01-06 19:14:20
  • Acid-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Acid-PEG13-NHS ester
Synonyms MFCD27952889
Description Acid-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C34H61NO19
Molecular Weight 787.84