Acid-PEG13-NHS ester

Modify Date: 2024-01-06 19:14:20

Acid-PEG13-NHS ester Structure
Acid-PEG13-NHS ester structure
Common Name Acid-PEG13-NHS ester
CAS Number 2152679-62-2 Molecular Weight 787.84
Density N/A Boiling Point N/A
Molecular Formula C34H61NO19 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Acid-PEG13-NHS ester


Acid-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Acid-PEG13-NHS ester
Synonym More Synonyms

 Acid-PEG13-NHS ester Biological Activity

Description Acid-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C34H61NO19
Molecular Weight 787.84

 Synonyms

MFCD27952889