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2055013-49-3

2055013-49-3 structure
2055013-49-3 structure
  • Name: Ald-Ph-PEG6-t-butyl ester
  • Chemical Name: Ald-Ph-PEG6-Boc
  • CAS Number: 2055013-49-3
  • Molecular Formula: C27H43NO10
  • Molecular Weight: 541.63
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 09:03:26
  • Modify Date: 2024-01-09 18:52:03
  • Ald-Ph-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Ald-Ph-PEG6-Boc
Synonyms MFCD28155204
Description Ald-Ph-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C27H43NO10
Molecular Weight 541.63