439114-12-2
439114-12-2 structure
- Name: Bis-PEG6-t-butyl ester
- Chemical Name: tert-Butyl 3-[2-(2-{2-[2-(2-tert-butoxycarbonylethoxy)ethoxy]ethoxy}ethoxy) -ethoxy]propionate
- CAS Number: 439114-12-2
- Molecular Formula: C22H42O9
- Molecular Weight: 450.56300
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2016-06-17 19:46:46
- Modify Date: 2024-01-17 15:49:58
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Bis-PEG6-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | tert-Butyl 3-[2-(2-{2-[2-(2-tert-butoxycarbonylethoxy)ethoxy]ethoxy}ethoxy) -ethoxy]propionate |
|---|---|
| Synonyms | MFCD18916981 |
| Description | Bis-PEG6-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C22H42O9 |
|---|---|
| Molecular Weight | 450.56300 |
| Exact Mass | 450.28300 |
| PSA | 98.75000 |
| LogP | 2.53300 |
| Precursor 0 | |
|---|---|
| DownStream 1 | |
