2364591-79-5

2364591-79-5 structure
2364591-79-5 structure
  • Name: DBCO-PEG1-amine
  • Chemical Name: DBCO-PEG1-amine
  • CAS Number: 2364591-79-5
  • Molecular Formula: C23H25N3O3
  • Molecular Weight: 391.46
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 22:13:20
  • Modify Date: 2024-01-16 15:57:30
  • DBCO-PEG1-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name DBCO-PEG1-amine
Description DBCO-PEG1-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C23H25N3O3
Molecular Weight 391.46