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1895922-70-9

1895922-70-9 structure
1895922-70-9 structure
  • Name: Fmoc-aminooxy-PEG4-acid
  • Chemical Name: Fmoc-aminooxy-PEG4-acid
  • CAS Number: 1895922-70-9
  • Molecular Formula: C26H33NO9
  • Molecular Weight: 503.54
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 14:20:30
  • Modify Date: 2024-01-10 10:47:49
  • Fmoc-aminooxy-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Fmoc-aminooxy-PEG4-acid
Synonyms MFCD29764345
Description Fmoc-aminooxy-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C26H33NO9
Molecular Weight 503.54