99365-23-8

99365-23-8 structure

Name: Prosaikogenin G
Chemical Name: Prosaikogenin G
CAS Number: 99365-23-8
Molecular Formula: C₃₆H₅₈O₈
Molecular Weight: 618.84
Catalog: Research Areas Metabolic Disease
Create Date: 2021-01-18 07:16:00
Modify Date: 2024-01-12 12:08:22
Prosaikogenin G, isolated from the roots of Buleurum bicaule Helm (Apiaceae), exhibits significant inhibitory effects on rat mesangial cell proliferation induced by Ang II. Prosaikogenin G has protective action on the kidney[1]. Prosaikogenin G is a derivative of Saikosaponin d in the gastrointestinal tract[2].

Name	Prosaikogenin G

Description	Prosaikogenin G, isolated from the roots of Buleurum bicaule Helm (Apiaceae), exhibits significant inhibitory effects on rat mesangial cell proliferation induced by Ang II. Prosaikogenin G has protective action on the kidney[1]. Prosaikogenin G is a derivative of Saikosaponin d in the gastrointestinal tract[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vitro	Prosaikogenin G (25, 50 μM) has protective action on the kidney for their down-regulated activity to the rat mesangial cell line (MC) proliferation induced by Ang II (1 μM), and does not exhibit injury to the normal MC[1].
References	[1]. Nan Xu, et al. A new saikogenin from the roots of Bupleurum bicaule. Chin J Nat Med. 2014 Apr;12(4):305-8. [2]. Pei Yu, et al. In vitro metabolism study of saikosaponin d and its derivatives in rat liver microsomes. Xenobiotica. 2017 Jan;47(1):11-19.

Molecular Formula	C₃₆H₅₈O₈
Molecular Weight	618.84

Hazard Codes	Xi