Prosaikogenin G

Modify Date: 2024-01-12 12:08:22

Prosaikogenin G Structure
Prosaikogenin G structure
Common Name Prosaikogenin G
CAS Number 99365-23-8 Molecular Weight 618.84
Density N/A Boiling Point N/A
Molecular Formula C36H58O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Prosaikogenin G


Prosaikogenin G, isolated from the roots of Buleurum bicaule Helm (Apiaceae), exhibits significant inhibitory effects on rat mesangial cell proliferation induced by Ang II. Prosaikogenin G has protective action on the kidney[1]. Prosaikogenin G is a derivative of Saikosaponin d in the gastrointestinal tract[2].

 Names

Name Prosaikogenin G

 Prosaikogenin G Biological Activity

Description Prosaikogenin G, isolated from the roots of Buleurum bicaule Helm (Apiaceae), exhibits significant inhibitory effects on rat mesangial cell proliferation induced by Ang II. Prosaikogenin G has protective action on the kidney[1]. Prosaikogenin G is a derivative of Saikosaponin d in the gastrointestinal tract[2].
Related Catalog
In Vitro Prosaikogenin G (25, 50 μM) has protective action on the kidney for their down-regulated activity to the rat mesangial cell line (MC) proliferation induced by Ang II (1 μM), and does not exhibit injury to the normal MC[1].
References

[1]. Nan Xu, et al. A new saikogenin from the roots of Bupleurum bicaule. Chin J Nat Med. 2014 Apr;12(4):305-8.

[2]. Pei Yu, et al. In vitro metabolism study of saikosaponin d and its derivatives in rat liver microsomes. Xenobiotica. 2017 Jan;47(1):11-19.

 Chemical & Physical Properties

Molecular Formula C36H58O8
Molecular Weight 618.84

 Safety Information

Hazard Codes Xi