581098-48-8
581098-48-8 structure
- Name: p38 MAP Kinase Inhibitor III
- Chemical Name: (S)-p38 MAP Kinase Inhibitor III
- CAS Number: 581098-48-8
- Molecular Formula: C23H21FN4S
- Molecular Weight: 404.503
- Catalog: Signaling Pathways MAPK/ERK Pathway p38 MAPK
- Create Date: 2021-05-16 09:33:27
- Modify Date: 2024-01-11 13:05:08
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p38 MAP Kinase Inhibitor III (compound 7h) is a p38 MAPK inhibitor with an 50 of 0.9 μM. p38 MAP Kinase Inhibitor III also inhibits IL-1β and TNF-α release with 50 values of 0.37 μM and 0.044 μM, respectively[1].
| Name | (S)-p38 MAP Kinase Inhibitor III |
|---|---|
| Synonyms |
(S)-p38 MAPK Inhibitor III
2-Pyridinamine, 4-[5-(4-fluorophenyl)-2-(methylthio)-1H-imidazol-4-yl]-N-[(1S)-1-phenylethyl]- 4-[5-(4-Fluorophenyl)-2-(methylsulfanyl)-1H-imidazol-4-yl]-N-[(1S)-1-phenylethyl]-2-pyridinamine |
| Description | p38 MAP Kinase Inhibitor III (compound 7h) is a p38 MAPK inhibitor with an 50 of 0.9 μM. p38 MAP Kinase Inhibitor III also inhibits IL-1β and TNF-α release with 50 values of 0.37 μM and 0.044 μM, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
p38 MAP kinase:0.9 μM (IC50) |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 589.4±60.0 °C at 760 mmHg |
| Molecular Formula | C23H21FN4S |
| Molecular Weight | 404.503 |
| Flash Point | 310.2±32.9 °C |
| Exact Mass | 404.147095 |
| LogP | 4.78 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.675 |