104676-09-7

104676-09-7 structure

Name: MCC
Chemical Name: MCC
CAS Number: 104676-09-7
Molecular Formula: C₁₂H₁₆N₂O₃
Molecular Weight: 236.27
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2021-09-09 11:58:22
Modify Date: 2024-01-12 11:36:01
MCC is non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as MCC-DM1[1].

Name	MCC

Description	MCC is non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as MCC-DM1[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
In Vitro	Antibody-drug conjugates (ADCs) are potent cytotoxic drugs linked to antibodies through chemical linkers, and allow specific targeting of drugs to neoplastic cells. Anti-CD22-MCC-DM1 is broadly effective in vitro against multiple NHL cell lines[1].
References	[1]. Polson AG, et al. Anti-CD22-MCC-DM1: an antibody-drug conjugate with a stable linker for the treatment of non-Hodgkin's lymphoma. Leukemia. 2010;24(9):1566-1573.