890152-41-7

890152-41-7 structure
890152-41-7 structure
  • Name: t-Boc-N-amido-PEG5-acetic acid
  • Chemical Name: BocNH-PEG5-acid
  • CAS Number: 890152-41-7
  • Molecular Formula: C17H33NO9
  • Molecular Weight: 395.45
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2022-04-01 10:09:07
  • Modify Date: 2024-01-21 11:16:21
  • BocNH-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name BocNH-PEG5-acid
Synonyms 2,2-Dimethyl-4-oxo-3,8,11,14,17,20-hexaoxa-5-azadocosan-22-oic acid, Boc-NH-PEG5-CH2COOH
Description BocNH-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Molecular Formula C17H33NO9
Molecular Weight 395.45