2055040-78-1

2055040-78-1 structure

Name: t-Boc-N-amido-PEG5-NHS ester
Chemical Name: Boc-N-PEG5-C2-NHS ester
CAS Number: 2055040-78-1
Molecular Formula: C₂₂H₃₈N₂O₁₁
Molecular Weight: 506.54
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-27 11:20:23
Modify Date: 2024-01-16 21:08:44
Boc-N-PEG5-C2-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	Boc-N-PEG5-C2-NHS ester
Synonyms	MFCD29764335

Description	Boc-N-PEG5-C2-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.