1260092-55-4

1260092-55-4 structure
1260092-55-4 structure
  • Name: t-Boc-N-amido-PEG1-NHS ester
  • Chemical Name: Boc-N-PEG1-C2-NHS ester
  • CAS Number: 1260092-55-4
  • Molecular Formula: C14H22N2O7
  • Molecular Weight: 330.33
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 08:30:57
  • Modify Date: 2024-01-07 08:23:45
  • Boc-N-PEG1-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Boc-N-PEG1-C2-NHS ester
Synonyms MFCD20227793
Description Boc-N-PEG1-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C14H22N2O7
Molecular Weight 330.33