Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Boc-NH-PEG2-C2-NHS ester
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: t-Boc-N-amido-PEG2-NHS ester
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

2183440-73-3

2183440-73-3 structure

2183440-73-3 structure

Name: t-Boc-N-amido-PEG2-NHS ester
Chemical Name: Boc-NH-PEG2-C2-NHS ester
CAS Number: 2183440-73-3
Molecular Formula: C₁₆H₂₆N₂O₈
Molecular Weight: 374.39
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 16:32:08
Modify Date: 2024-01-08 13:22:18
Boc-NH-PEG2-C2-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Boc-NH-PEG2-C2-NHS ester
Synonyms	MFCD31381627

Description	Boc-NH-PEG2-C2-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₆H₂₆N₂O₈
Molecular Weight	374.39