1613480-70-8

1613480-70-8 structure
1613480-70-8 structure
  • Name: Cholesterol 24-hydroxylase-IN-1
  • Chemical Name: Cholesterol 24-hydroxylase-IN-1
  • CAS Number: 1613480-70-8
  • Molecular Formula: C17H23N5O
  • Molecular Weight: 313.40
  • Create Date: 2022-06-18 22:24:08
  • Modify Date: 2024-01-21 14:45:42
  • Cholesterol 24-hydroxylase-IN-1 (compound 17) is a potent, orally active, and highly selective cholesterol 24-hydroxylase (CH24H or CYP46A1) inhibitor (IC50=8.5 nM). Cholesterol 24-hydroxylase-IN-1 can cross blood-brain barrier[1].

Name Cholesterol 24-hydroxylase-IN-1
Description Cholesterol 24-hydroxylase-IN-1 (compound 17) is a potent, orally active, and highly selective cholesterol 24-hydroxylase (CH24H or CYP46A1) inhibitor (IC50=8.5 nM). Cholesterol 24-hydroxylase-IN-1 can cross blood-brain barrier[1].
Related Catalog
References

[1]. Kajita Y, et al. Discovery of Novel 3-Piperidinyl Pyridine Derivatives as Highly Potent and Selective Cholesterol 24-Hydroxylase (CH24H) Inhibitors. J Med Chem. 2022;65(4):3343-3358.

Molecular Formula C17H23N5O
Molecular Weight 313.40